Next Generation Sequencing (NGS) Market
The next generation sequencing market is rapidly evolving with a large number of developments taking place to increase accuracy and speed, and reduce costs of sequencing. It is the fastest-growing and most lucrative segment in the genomics space with an estimated growth of 16.3%. The global NGS market was valued at $1.3 billion in 2012 and is poised to reach $2.7 billion by 2017. By supporting genomics research, various government bodies like NHGRI (National Human Genome Research Institute, U.S.) and Biotechnology and Biological Sciences Research Council (BBSRC, U.K.) are increasing the adoption of high-throughput sequencing platforms.
The growth of the overall NGS market is driven by continuous innovations and
developments in the market aimed at higher throughput, increased accuracy, and
affordable costs. However, factors such as high reliability on grants and
funding from the government, and decrease in capital expenditure from academic
institutions are hindering the growth of the market. In addition, the
interpretation of big data generated by sequencers and the subsequent storage
and management of the analyzed data is still a challenge. Owing to the
complexity of NGS technologies and data, standardization of the overall NGS
workflow presents an unmet need. The opportunities for the growth of this market
include developments in the pre-sequencing, cloud computing, and NGS
bioinformatics solutions.
The NGS platforms market was dominated by Illumina in 2012, which accounted for
the largest market share of 56%. Other companies with commercial platforms
include Life Technologies (U.S.), 454 Roche (U.S.), and Pacific Biosciences
(U.S.). The recently introduced Bench-top and NGS platforms will drive the
market. Based on steps in the NGS workflow, the overall NGS market has three
major segments, namely, pre-sequencing, NGS platforms and services, and NGS data
analysis, storage and management.
The raw sequencing data generated by today’s sequencers does not reflect on any
meaningful information in itself. Also, open source tools for analyzing NGS data
require adequate bioinformatics training. These factors open up huge
opportunities for commercial NGS bioinformatics software, workbenches, and
services, whose market is currently fragmented and has a relatively smaller
size. Whole genome sequencing, targeted re-sequencing, de novo sequencing, RNA-Seq,
ChIP-Seq and methyl-Seq are the major applications that use NGS data analysis
tools and services. Key players like CLC bio (Denmark), Biomatters (New
Zealand), Partek (U.S.), Genomatix (Germany), Knome (U.S.), and DNASTAR (U.S.)
dominate this market space.
Next generation sequencing is set to revolutionize applied markets like
diagnostics, drug discovery, biomarker discovery, personalized medicine, and
agriculture and animals research. Research institutes and government bodies
contribute the highest to the end-user market of NGS; however, the adoption rate
in hospitals will increase in the near future due to cost effectiveness, high
throughput, and sensitivity.
The NGS market will witness a whole new generation of sequencing platforms based
on nanapore sequencing technology and fully integrated instruments that could
perform all the NGS workflow steps.
Scope of the Report
This research report categorizes and analyzes the global NGS market on the basis
of steps in the NGS workflow and NGS applications. These markets are further
divided into segments and sub-segments, to provide exhaustive value analysis for
the years 2010, 2011, 2012, and forecast to 2017. Each market is comprehensively
analyzed at a granular level by geography (North America, Europe, Asia, and Rest
of the World) to provide in-depth information on the global scenario.
Global NGS market, by steps in workflow
Pre-sequencing Products and Services
DNA fragmentation and size selection
Library preparation
Target enrichment
Quality control
Sequencing Platforms, Consumables/Reagents and Services
Illumina
HiSeq Series
Genome Analyzer IIx
HiScanSQ
MiSeq
Life Technologies
SOLiD Series
Ion PGM (Personal Genome Machine)
Ion Proton
454 Lifesciences (Roche)
GS Junior
GS FLX+
Pacific Biosciences
PacBio RS II
Others
Sequencing Services
NGS Data Analysis/Bioinformatics
By product
NGS data analysis software and workbenches
NGS data analysis services
NGS storage management and cloud computing solutions
By application
Whole Genome Sequencing
Targeted Resequencing
De novo Sequencing
RNA-Seq
ChIP-Seq
Methyl-Seq
Others
Global NGS market, by Technology
Sequencing by synthesis (SBS)
Ion semiconductor sequencing
Sequencing by ligation (SBL)
Pyrosequencing
Single molecule, real-time (SMRT) Sequencing
Global NGS market, by Application
Diagnostics
Drug Discovery
Biomarker Discovery
Personalized Medicine
Agriculture and Animal Research
Others
NGS market, by Geography
North America
Europe
Asia
RoW (Africa, LATAM, Middle-East, Pacific countries)